Causes of Thyrotoxicosis

Causes of Thyrotoxicosis

Causes of Thyrotoxicosis

Causes of Thyrotoxicosis

  1. Circulating Thyroid Stimulators
  2. —Graves’Disease ( TSH receptor Antibody)
  3. Inappropriate TSH Syndromes—-TSH pituitary tumor—Pituitary resistance syndrome
  4. Pregnancy related syndromes— HCG or mutant TSHR hypersensitive to HCG
  5. Autonomous thyroid function—Toxic nodule,MNGoiter, and non-autoimmune hyperthyroidism—TSH receptor activation
  6. Low uptake hyperthyroidism—postpartum,silent thyroidits subacute thyroditis, acute infections, high dose Xray Rx —-release of stored hormone
  7. Miscellaneous—Surgery—release of hormone,infarct—-release,excess exogenous thyroid hormone —-too much medication, metastatic thyroid cancer—- foci of functioning cancer,struma ovarii—ovarian teratoma
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