Hypothyroidism 101: Does LT4 Correct All Aspects of Hypothyroidism?
JCEM Dec 2018 103(12) 4533-42
E.A. McAninch et al
- Monotherapy with LT4 only failed to correct the Low density lipoprotein LDL and total cholesterol TC.
- All other markers tested normalized with LT4.
- No one knows if this small amount of LDL or TC is clinically significant.
- Before changing to combination T4/T3 therapy more studies have to show it is significant.
- Also other biologic markers need to be studied before any change in recommendations for treatment.