Pregnancy and Thyroid Disease #1

Pregnancy and Thyroid Disease #1

Pregnancy and Thyroid Disease #1

Pregnancy and Thyroid Disease #1

Thyroid enlarges in pregnancy. Iodine needs increase 50%. 18% of the pregnant have thyroid antibodies which can alter the outcomes of the pregnancy for mother and fetus. Presence of antibodies increases risk of thyroid dysfunction during and post- partum. Birth defects have been linked to both anti-thyroid drugs. methimazole (MMI) and propylthiouracil (PTU) in treatment of Graves’.Treatment during breast feeding is still in question on the drugs. Screening potential pregnant for antibodies and TSH is still not recommended due to costs. During pregnancy women have lower TSH with 15% below TSH of 0.4 mU/L during first trimester.10% in second and 5%  in third. Free T4 decreases by third trimester. TSH normal range in first trimester  0.1-1.0. Free T4 during pregnancy needs to be based on each assay data normal pregnancy ranges. Total T4 is very accurate way to assess thyroid horome during pregnancy

 

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