Thyroid in Pregnancy 101:Serum TSH How, when and why?

Thyroid in Pregnancy 101:Serum TSH How, when and why?

Thyroid in Pregnancy 101:Serum TSH How, when and why?
Thyroid in Pregnancy 101:Serum TSH How, when and why?
Serum TSH determinations in pregnancy: How, when and why?
  • September 2010
  • Nature Reviews Endocrinology 6(9):526-9

Comments by Dr.Guttler

  1. TSH is the first line thyroid function test in pregnancy.
  2. A single serum TSH is the most sensitive index of thyroid function.
  3.  Normal thyroid function is important to ensure the best possible pregnancy outcome.
  4.  Thyroid diseases are relatively frequent in women of childbearing age.
  5.  TSH can detect subtle thyroid function abnormalities in pregnancy.
  6. Such as overt and subclinical hypothyroidism and hyperthyroidism.
  7. Poor pregnancy outcomes occur with all thyroid function abnormalities.
  8.  TSH should be drawn in all pregnant women.
  9. What to do in clinical practice?
  10. Abnormal TSH is the clue to get FreeT4, FreeT3 and Thyroid Antibodies for autoimmune disease and subclinical hypo or hyperthyroidism.
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