Be Aware of Afirma GEC Suspicious Result in Indeterminate Thyroid Nodules. Many More Are Not Cancer, But the look alike Benign Noninvasive Follicular Neoplasm with Papillary-like Nuclei called NIFN-P.

Be Aware of Afirma GEC Suspicious Result in Indeterminate Thyroid Nodules. Many More Are Not Cancer, But the look alike Benign Noninvasive Follicular Neoplasm with Papillary-like Nuclei called NIFN-P.

Be Aware of Afirma GEC Suspicious Result in Indeterminate Thyroid Nodules. Many More Are Not Cancer, But the look alike Benign Noninvasive Follicular Neoplasm with Papillary-like Nuclei called NIFN-P.

Be Aware of Afirma GEC Suspicious Result in Indeterminate Thyroid Nodules. Many More Are Not Cancer, But the look alike Benign Noninvasive Follicular Neoplasm with Papillary-like Nuclei called NIFN-P.

Cancer Cytopathology 2017 published online

Hang JF et al

 

thyroid-cancer-shown

  1. 384 suspicious nodules had GEC suspicious results.
  2. 177 had a thyroidectomy.
  3. Re-classified NIFT-P cases caused the positive predictive value to decrease from 42% to 24% in AUS and 24% to 13 % in SFN group.
  4. Too many total thyroidectomies were done with GEC  suspicious result compared to lobectomy.
  5. REclasification of NIFT-P has made GEC suspicious less valuable as it’s ability to diagnose cancer is significantly decreased.
  6. While many still need surgery, most would only need a lobe rather than a total.
  7. With improved diagnosis of NIFT-P on the needle biopsy specimens the need for diagnostic lobectomy would be unnecessary.
  8. The risk of complications from a total thyroidectomy for a benign condition would not occur.

thyroid-surgery-complications

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