Thyroid Cancer 101: Persistence of Thyroglobulin Antibody (TG AB ) for Years Not A Sign of Recurrence.

Thyroid Cancer 101: Persistence of Thyroglobulin Antibody (TG AB ) for Years Not A Sign of Recurrence.

Thyroid Cancer 101: Persistence of Thyroglobulin Antibody (TG AB ) for Years Not A Sign of Recurrence.

Thyroid Cancer 101: Persistence of Thyroglobulin Antibody (TG AB ) for Years Not A Sign of Recurrence.

Martone A  et al

Thyroid 28(7) 2018 p.871

Dr.Guttler’s comments on this article.

  1. It takes years for the TGAB to decline in patients with thyroid cancer treated with total thyroidectomy and no RAI/131.
  2. Lymphocytic infiltration and slow the decline.
  3. Elevation of TGAB late may be recurrence  or just be regrowth of normal thyroid not cancer.
  4. TGAB  at first post op visit of < 60 was a good indicator of disappearance of
    TGAB by 6 years.

Persistent cancer marker TGAB should not be used to give radioiodine or more surgery

thyroid-surgery-complications

if it is declining over 6 years. Rising TGAB can still be just regrowth of thyroid tissue not cancer.

All 107 patients were  recurrence free at 6 years.

Call me for evaluation before anymore surgery or radiation.

310-393-8860

or

thyroid.manager@protonmail.com

 

DR.G.

 

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