Thyroid Cancer Alternative Therapy 101: Percutaneous Ethanol Injection PEI vs Re-operation for Locally Recurrent Thyroid cancer .
Tatyana E. Fontenot,et al
JAMA Otolaryngol Head Neck Surg. 2015;141(6):512-518.
- Reoperation for recurrent papillary thyroid cancer (PTC) can be associated with a high rate of complications and failure to provide lasting remission.
- Percutaneous ethanol injection (PEI) may be an effective nonsurgical management option for locally recurrent PTC.
- Recurrent thyroid cancer in a neck lymph node for PEI.
- 27 studies met the inclusion criteria.
- .A total of 1617 patients were included in this analysis.
- 168 (11.4%) were treated with PEI, and 1449 (88.6%) were treated with reoperation.
- Re-operation was successful in 94.8% of cases.
- 87.5% success rate for PEI
- The recurrence rates for PEI and re-operation at the site of the treated lesion or elsewhere in the neck were also similar.
- Re-operation was associated with a 3.5% pooled risk of complications.
- PEI incurred a pooled risk of 1.2%.
- Although presently inferior to re-operation, PEI has the potential to be a widely accepted and effective nonsurgical treatment option for limited recurrent PTC in poor surgical candidates or patients seeking to avoid multiple re-operations.
- I do PEI for not only benign thyroid nodules but also for recurrent local lymph node recurrence without surgery.
- Call me at 310-393-8860 or firstname.lastname@example.org for details before you have another neck dissection.