1.To minimize potential harm from overuse of fine-needle aspiration, Thyroid Imaging Reporting and Data Systems (TIRADSs) were developed for thyroid nodule risk stratification.
2.The purpose of this study was to perform validation of three scoring risk stratification models for thyroid nodules using ultrasonography features, a web-based malignancy risk stratification system at website (http://www.gap.pe.kr/thyroidnodule.php) and those developed by the Korean Society of Thyroid Radiology (KSThR) and the American College of Radiology (ACR).
3.Thyroid nodules according to the following criteria: internal content, echogenicity of the solid portion
, shape, margin
Lymph node with abnormal shape and blood flow.
4. 954 patients (mean age, 50.8 years; range, 13-86 years) with 1112 nodules were evaluated in our institute from January 2013 to December 2014.
5. Thyroid malignancy was present in 37.2% of nodules (414/1112).
6. According to the 14-point web-based scoring risk stratification system, malignancy risk ranged from 4.5% to 100.0% and was positively associated with an increase in risk scores.
7. The web-based scoring system showed the best-calibrated result with a p value of 0.078.
8.The three scoring risk stratification models using the ultrasonography features of thyroid nodules to stratify malignancy risk showed acceptable predictive accuracy and similar areas under the curve.
9.The web-based scoring system demonstrated the strongest agreement in calibration ability analysis.
10.The easily accessible automated web-based scoring risk stratification system may overcome the complexity of the various TIRADS guidelines and provide simplified guidance on personalized and optimal management in real practice.