Thyroid Nodules and Cancer in Children 101
Comments by Dr.G. on the incidence in children.
1. New cases of thyroid cancer in people age <20 represent 1.8% of all thyroid malignancies diagnosed in the United States. ncbi.nlm.nih.gov/pmc/articles/PMC4854274
2.The incidence appears to be increasing .ncbi.nlm.nih.gov/pmc/articles/PMC4854274
3. 15- to 19-year-old adolescents, thyroid cancer is the eighth most frequently diagnosed cancer and the second most common cancer among girls. 18).ncbi.nlm.nih.gov/pmc/articles/PMC4854274, ncbi.nlm.nih.gov/pmc/articles/PMC4854274
4.Adolescents have a 10-fold greater incidence than younger children, and there is a female to male preponderance (5:1) during adolescence that is not seen in young children.
5.The most common presentation for DTC in children is that of a thyroid nodule.
6. Papillary thyroid cancer (PTC) also frequently presents as cervical adenopathy with or without a palpable thyroid lesion, or as an incidental finding after imaging or surgery for an unrelated condition.ncbi.nlm.nih.gov/pmc/articles/PMC4854274
7. The diagnosis is made sometimes only after the discovery of distant metastases.