Thyroid Tumor RFA 101: What Went Wrong in 2001 That Has Delayed RFA Development in the USA?

Thyroid Tumor RFA 101: What Went Wrong in 2001 That Has Delayed RFA Development in the USA?

Thyroid Tumor RFA 101: What Went Wrong in 2001 That Has Delayed RFA Development in the USA?

Background. Regional recurrence of well-differentiated thyroid cancer (WTC) is primarily detected with ultrasonography (US), and current treatment is surgical. Radiofrequency ablation (RFA) has been used primarily for liver tumors as an alternative to a surgical procedure. We have applied RFA to a group of patients with locally recurrent WTC. Methods. Eight patients underwent percutaneous RFA for biopsy-proven recurrent WTC in the neck (mean size, 2.4 cm; range, 0.8-4.0 cm) while under intravenous conscious sedation and with US guidance. The RF electrode was inserted into the site of recurrence and treated with the maximum allowable current for between 2 and 12 minutes. Follow-up consisted of US in 8 patients, thyroglobulin levels in 6 patients, biopsy in 4 patients, and surgical treatment in 2 patients. Results. All 8 patients with no bleeding or infectious complications were treated as outpatients. A minor skin burn and 1 vocal cord paralysis occurred. No recurrent disease at the treatment site was detected, with a mean follow-up of 10.3 months. Histological examination showed no evidence of a tumor in the treated lymph nodes in 6 patients. Follow-up US examinations showed disappearance of previously detected color Doppler flow, as well as mass shrinkage and internal cystic change, or both. Conclusions. US-guided RFA is an exciting new treatment modality that appears to have a future role in treating locally recurrent WTC. (Surgery 2001;130:971-7.)

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The left is the large bore #17 gauge lone electrode used in this 2001 study.

The right is the Thyroid RF mini-probe that is short for work in the neck

and has smaller bore of #18 and 19 gauge.

The Thyroid RF mini probe come in different size burn areas. The picture shows a 10 mm burn area

on a cow liver surface. 3, 5. and 7 mm burn areas are also coming to the USA.page-7-2

 

 

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