Can HIFU Improve Symptoms, and Decrease the Volume of the Thyroid Nodule? This study suggests the answer is yes
High-Intensity Focused Ultrasound for Treatment of Symptomatic Benign Thyroid Nodules: A Prospective Study.
Twenty-two patients underwent HIFU and 22 underwent active surveillance.The 12-month mean volume reduction was significant (68.87% ± 15.27 [range, 47.35%-94.89%], P < .001). But not in the surveillance group (-2.11% ± 6.29 [range, -15.64% to 12.70%], P > .05). At 12 months, patients in the HIFU group had less swelling (P < .001), lower pressure symptom scores (P < .001), and higher physical composite scores (P = .006). Physical composite scores significantly correlated with 6-month reduction in nodule size (r = 0.768; 95% CI: 0.660, 0.930; P < .001) and 12-month reduction in nodule size (r = 0.704; 95% CI: 0.680, 940; P < .001). Conclusion HIFU ablation of symptomatic benign thyroid nodules not only induced significant shrinkage but also improved pressure symptom scores and HRQOL throughout a 12-month period.
The system uses 2 ultrasound systems.One is the usual diagnostic US that will measure the nodule and the computer will map the nodule and “danger areas”. The second is a treatment US that will deliver the heat to a designated path through the nodule. The key is the fact there is no puncture of the skin to position the probe as in Radiofrequency or microwave ablation.
HIFU is a true non-invasive method from France that uses skin contact just like diagnostic to do the ablation. The 2 US beams meet at a focal point and that is where the heat causes the destruction of the nodules. HIFU is not approved in the USA, but I can arrange to have you treated in Europe after my evaluation in the US. The 2 day stay would just for the treatment as the my evaluation will be accepted so the actual stay in country will be short. Call Matt if you are interested in a HIFU treatment referral to Europe. 310-393-8860
Richard Guttler MD,FACE,ECNU