Thyroid No surgery 101:Radiofrequency ablation RFA for benign thyroid nodules according to different US features: an Italian multicentre prospective study.

Thyroid No surgery 101:Radiofrequency ablation RFA for benign thyroid nodules according to different US features: an Italian multicentre prospective study.

Thyroid No surgery 101:Radiofrequency ablation RFA for benign thyroid nodules according to different US features: an Italian multicentre prospective study.
Thyroid No Surgery 101:
Dr. Guttler’s comments:
nodules
1. 340 patients with solid benign nodules.
2. 21 ml volume decreased to 6 ml by 12 months.
3. Spongiform nodules responded the best with  76 % reduction.
4. Other patterns decreased less at  67 % decrease.
5. Mean symptoms/cosmetic scores were significantly reduced in all patients.
6.No major complications were encountered.
complications
us
Ethanol PEI and thyroid RFA ablations are safe and not painful and can replace surgery in patients with benign nodules with symptoms. These can reduce or get rid of the symptoms of large nodules.
Call me for details on both PEI and thyroid RFA.
310-393-8860 or email to thyroid.manager@protonmail;.com.
PEI in my office and a evaluation to see if you are a candidate to have Thyroid RFA.
Dr.G.
Radiofrequency ablation RFA for benign thyroid nodules according to different US features: an Italian multicentre prospective study.
Eur J Endocrinol. 2018 Nov 1. pii: EJE-18-0685.R1. doi: 10.1530/EJE-18-0685. [Epub ahead of print]
Deandrea M et al
BACKGROUND:
The purpose of this study was to confirm the generalisation of radiofrequency ablation (RFA) in the treatment of benign thyroid nodules (BTN) and to look for a correlation between final shrinkage and some US findings in a large Italian population data set.
METHODS:
This prospective study included 337 patients with solid cold BTN from six Italian institutions. Nodule volume, US pattern, thyroid function, symptom/cosmetic scores and complications were evaluated before and at 6 and 12 months. The primary outcome was to find a correlation between basal volume and US pattern of the nodules and final shrinkage. The secondary outcome was to confirm the efficacy and safety of RFA in a large data set.
RESULTS:
The median basal volume was 20.7ml which significantly decreased after RFA at 6 months (7.3ml (-63.5%), p<0.001) and at 12 months (6ml (-70%), p vs 6 months=0.009). A significant correlation was found for US structure (a spongiform pattern showing a 76% reduction vs 67% and 66% of mix and solid patterns respectively, p<0.01) as well as for vascularity (intense peripheral and intranodal patterns showing 71% vs 68% and 67% of weak peripheral and intranodal and peripheral patterns respectively, p<0.03), but not for macrocalcifications. A slight inverse correlation was found between nodule basal volume and shrinkage (Spearman -0.23). Mean symptoms/cosmetic scores were significantly reduced. No major complications were encountered.
CONCLUSIONS:
This multicentre study validated the efficacy and safety of RFA for treating BTN and showed a clear correlation between final shrinkage and some common US findings.
Add Your Comment

Contact Info
1328 16th Street, Santa Monica, CA 90404
Monday – Friday
9:00 AM to 5:00 PM
(310) 393-8860