Afirma GEC

Afirma GEC

Afirma GEC

Afirma GEC Beware of small numbers in studies so far.

Afirma has a strong negative predictive value for benign. This is a major use .

 Large multicenter study, multiple exclusions, variable performance in meta-analysis. No data in types of cancer in  Bethesda III IV Cancer cohorts.Validation still small. Afirma has limitations. Afirma has not shown efficacy in Hurthle cell neoplasms HCN . Positve predictive value is poor for HCN.

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