Why We Don’t Use Stimulated Thyroglobulin TG in Follow up of Thyroid Cancer: Neck Ultrasound and Suppressed TG Are Good Enough

Why We Don’t Use Stimulated Thyroglobulin TG in Follow up of Thyroid Cancer: Neck Ultrasound and Suppressed TG Are Good Enough

Why We Don’t Use Stimulated Thyroglobulin TG in Follow up of Thyroid Cancer: Neck Ultrasound and Suppressed TG Are Good Enough

Why We Don’t Use Stimulated Thyroglobulin TG in Follow up of Thyroid Cancer: Neck Ultrasound and Suppressed TG Are Good Enough

Neck Sonography and Suppressed Thyroglobulin Have High Sensitivity for Identifying Recurrent/Persistent Disease in Patients With Low-risk Thyroid Cancer Treated With Total Thyroidectomy and Radioactive Iodine Ablation, Making Stimulated Thyroglobulin Unnecessary.
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In low-risk thyroid cancer treated with total thyroidectomy and radioiodine, sonography and suppressed or stimulated Tg have similar negative predictive values for persistence/recurrence. Importantly, the coexistence of negative sonographic findings and suppressed Tg lower than 1 ng/mL makes the addition of stimulated Tg unlikely to identify clinically important disease.

Comment: The USC thyroid cancer team using DR Carole Spencer’s TG have used suppressed TG form years without stimulated values.

Richard Guttler MD,FACE.ECNU

thyroid.com

 

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