Why We Don’t Use Stimulated Thyroglobulin TG in Follow up of Thyroid Cancer: Neck Ultrasound and Suppressed TG Are Good Enough
In low-risk thyroid cancer treated with total thyroidectomy and radioiodine, sonography and suppressed or stimulated Tg have similar negative predictive values for persistence/recurrence. Importantly, the coexistence of negative sonographic findings and suppressed Tg lower than 1 ng/mL makes the addition of stimulated Tg unlikely to identify clinically important disease.
Comment: The USC thyroid cancer team using DR Carole Spencer’s TG have used suppressed TG form years without stimulated values.
Richard Guttler MD,FACE.ECNU