Thyroid No Surgery 101: Ethanol Ablation in Renal Failure Patients:Endocrinologists Need to Think About PEI in Secondary or Tertiary Hyperparathyroidism.
parathyroid hyperplasia due to renal failure
Ultrasound-guided percutaneous ethanol ablation of parathyroid hyperplasia: preliminary experience in patients on chronic dialysis.
Ultrasonography-guided, percutaneous ethanol ablation (PEA) of hyperplastic parathyroid glands in chronic dialysis patients suffering from secondary or tertiary hyperparathyroidism.
- Seventeen uraemic patients (mean age 52 +/- 14 years) with hypercalcaemia and elevated serum levels of parathyroid hormone were assessed for ethanol ablation.
- 10/17 patients did not fulfill the inclusion criteria and underwent surgical parathyroidectomy.
- 7/17 patients were treated using PEI.
- 3/7 patients underwent further ethanol ablation due to recurrent symptomatic hyperparathyroidism.
- Following the procedures, serum values of total calcium and parathyroid hormone remained within target range with concomitant medical therapy in all patients.
- PEI performed as a single-shot therapy can be used as a minimally invasive and safe supplement to medical therapy in the treatment of secondary or tertiary hyperparathyroidism in selected patients.
- In case of recurrence, treatment can be repeated without any problems.