Thyroid dysfunction we know as hypo and hyperthyroidism was not thought to be thyroid diseases when first described in the 19 th century. Instead a slow acquired evidence gradually defined the diseases. Coindet described thyrotoxicosis without realizing it.Parry, who saw it before Coindet but did not publish it in a journal but in an obscure book after he died. He described rapid heart beats,goiter, and bug eyes Early Graves’Disease.
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